From the US State Department's website:

Senior Travelers

Seniors should review the information contained in the section Planning Your Trip: Learn About the Places You Will Visit, consider the following tips, and discuss the trip with a physician:

Local conditions: Be aware of any effects the local topography or climate may have on you: If you are sensitive to altitude or to humidity, or to other attributes of your destination, consult with your physician.

Don’t over-program: The additional physical activity undertaken during travel can be quite strenuous, and sudden changes in diet and climate can have serious health consequences for the unprepared traveler.

Pack wisely: Don’t pack so much that you will end up lugging around heavy suitcases. Dress conservatively—a wardrobe that is flashy may attract the attention of thieves or con artists, while clothing that is very casual may result in being barred from some tourist sites overseas. Include a change of clothing in your carry-on luggage.

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Great tips! Especially the one about seeing your physician before you go.

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