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I think the main thing is once you have decided on the cruise line, ship and itinerary get as much info about your wife's condition and what it entails with, as Sue suggested, medical info/letter from your doctor and get into contact with the cruise line as soon as possible. If you give them everything upfront they are going to be more understanding of your circumstances and they in turn will be more than willing to accommodate you in any way they can and make your holiday as relaxing and enjoyable as possible.
One other tip I would suggest is that if you require a cabin set aside for disabled passengers rather than the standard cabins, get in there early and be insistant. They tend to go quickly and not always to passengers who really require the facilities within them. The cabins are larger and therefore are quite sought after for that reason.
On the links posted earlier the facilities are available and on each cruise line listed there are also individual ships, deckplans, photos of cabins etc. This will all help, along with everyone's advice here, to give you an insight into what to expect.
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